Southern Herbals Limited

Manufacturer of Fine Chemicals
 

Vincristine Sulfate Vinblastine Sulfate Teniposide Etoposide Paclitaxel
Podophyllotoxin Camptothecine Baccatin III 10-Deacetybaccatin III Colchicine
Belomycin* Doxorubicin* Capsaicin Forskolin Ajmalicine
  Sennosides Glymnemic Acid    
 PODOPHYLLOTOXIN
PHYSICAL PROPERTIES
 RAW MATERIAL Rhizome and roots of Podophyllum emodi wall (Bebendacae)
PREPARATION Total extractives using solvent, selective extraction, further processing and purification.
 PHYSICAL CHARACTERISTICS White  Crystalline Powder and very hygroscopic mp 110-116 deg.  C soluble in Chloroform-dried mp 177-182 deg. C 
CHEMICAL CHARACTERISTICS 
COMMON NAMES Podophyllotoxin, Podofilox, Condyline, Condylox, Wartec, Warticon.
CHEMICAL NAME (5R-(5a, 5ab, 8aa 9a)-5,8,8a,9-Tetrahytro-9-hydroxy-5{3,4,5-trimethoxyphenyl) furo ( 3’4’6’7) napththo(2,3-d)-1,3-dioxol-6(5aH)-one
MOLECULAR FORMULA C22 H22  08
MOLECULAR WEIGHT 414.40
IDENTIFICATION 
IR (KBr) 
UV (Max) 
Specific optical rotation 

 V max 1760, 1592, 1240 cm 
292 nm 
Between -129.0 -136.3 (Chloroform)
PURITY (HPLC) 95%  plus as specified.
TOXICITY Highly Toxic
USE Antineoplastic activity, in treatment if warts, Raw material for Etoposide and Teniposide.

Podophyllotoxin Podophyllotoxin Podophyllotoxin Podophyllotoxin Podophyllotoxin Podophyllotoxin Podophyllotoxin
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