CHEMICAL
CHARACTERISTICS
| COMMON NAMES |
Etoposide: EPEG; NSC-141540: VP -16-213; Lastet;
Vepesid |
| CHEMICAL NAME |
9-[( 4,6-0-Ethylidene-b-D-
glucopyranosyl) oxy] -5,8,8a,9-teetrahydro
5-(4-hydroxy-3,5-dimethoxyphenyl)furo(3’,4’6,7]
naptho[2,3-d]-1, 3-dioxol-6(5aH]-one |
| MOLECULAR FORMULA |
C29 H32 013 |
| MOLECULAR WEIGHT |
588.56 |
IDENTIFICATION
Specific Optical rotation |
-110.5 deg (Chloroform) |
| PURITY |
HPLC 96% |
| USE |
Anti cancer, Refractory testicular tumors, Small cell
iung Cancer. The Predominant effect of etoposide is
inhibation of DNA Synthesis resulting in arrest of cell
cycle. At high doses cells entering mitosis
are lysed. |
| PROPRITARY NAMES AND MANUFACTURERS |
Vumon (BMS), Lastet ( Nippon Hayaku) |
