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Southern Herbals Limited

Manufacturer of Fine Chemicals

Vincristine Sulfate	Vinblastine Sulfate	Teniposide	Etoposide	Paclitaxel
Podophyllotoxin	Camptothecine	Baccatin III	10-Deacetybaccatin III	Colchicine
Belomycin*	Doxorubicin*	Capsaicin	Forskolin	Ajmalicine
	Sennosides	Glymnemic Acid

CAMPTOTHECINE

**PHYSICAL PROPERTIES**
RAW MATERIAL	Nothapodytes foetida (wt) miers (Icainaceae)
PREPARATION	Total extractives of Powdered wood suing a solvent, further processing and purification.
PHYSICAL CHARACTERISTICS	Pale yellow coloured powder, mp 257-260 deg. C soluble in DMF (Dimethyl formamide)

**CHEMICAL CHARACTERISTICS**
COMMON NAMES	Camptothecine
CHEMICAL NAME	(S) 4-Ethyl-4-hydroxy-IH-Pyrano(3’4’6’7) indolizino (1,2,-b) quinoline 3,14 (4H, 12H)-dione
MOLECULAR FORMULA	C20 H16 N2 04
MOLECULAR WEIGHT	346.34
IDENTIFICATION IR (KBr) UV (Max) Specific Optical rotation	V max 3400 1745 1655 1605 & 1580 cm l max 220, 253 & 358 nm +31.3 deg. (in Chloroform-methanol)
PURITY USP Std	By HPLC 98% +.
TOXICITY	Highly Toxic
USE	Anti Cancer activity, Raw material for Topotecan, CPT-11.

Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine

International Recognition

Company profile

ksnmurthy@vsnl.com