Southern Herbals Limited

Manufacturer of Fine Chemicals

Vincristine Sulfate Vinblastine Sulfate Teniposide Etoposide Paclitaxel
Podophyllotoxin Camptothecine Baccatin III 10-Deacetybaccatin III Colchicine
Belomycin* Doxorubicin* Capsaicin Forskolin Ajmalicine
  Sennosides Glymnemic Acid    

 CAMPTOTHECINE

PHYSICAL PROPERTIES
 RAW MATERIAL Nothapodytes foetida (wt) miers (Icainaceae) 
PREPARATION Total extractives of Powdered wood suing a solvent, further processing and purification.
 PHYSICAL CHARACTERISTICS Pale yellow coloured powder, mp 257-260 deg. C soluble in DMF (Dimethyl formamide) 
CHEMICAL CHARACTERISTICS 
COMMON NAMES Camptothecine
CHEMICAL NAME (S) 4-Ethyl-4-hydroxy-IH-Pyrano(3’4’6’7) indolizino (1,2,-b) quinoline 3,14 (4H, 12H)-dione
MOLECULAR FORMULA C20 H16 N2 04 
MOLECULAR WEIGHT 346.34
IDENTIFICATION 
IR (KBr) 
UV (Max) 
Specific Optical rotation

V max 3400 1745 1655 1605 & 1580 cm 
l max 220, 253 & 358 nm 
+31.3 deg.  (in Chloroform-methanol)
PURITY 
USP Std
By HPLC 98% +.
TOXICITY Highly Toxic
USE Anti Cancer activity, Raw material for Topotecan, CPT-11.

Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine Camptothecine
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