Ajmalicine - Southern Herbals Limited

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Southern Herbals Limited

**PHYSICAL PROPERTIES**
RAW MATERIAL	Roots of Catharanthus Roseus
PREPARATION	Total extractives using solvent, selective extraction, further processing and purification.
PHYSICAL CHARACTERISTICS	Yellow Crystalline Powder mp 256-257 deg. C soluble in Chloroform, alcohol insoluble in pet.Ether.

**CHEMICAL CHARACTERISTICS**
COMMON NAMES	Ajmalicine/Raubasine, Tetrahydroserpentine, Circoline, Hydroserpan, Isoarteril, Lamuran, Py-Tetrahydroserpentine.
CHEMICAL NAME	(19a)-16, 17-Didehydro-19-methyloxayohimban-16- carboxylic acid methyl ester.
MOLECULAR FORMULA	C21 H24 N2 03
MOLECULAR WEIGHT	352.4
IDENTIFICATION UV (Max) Specific Optical rotation	227, 292 nm -60 deg. (Chloroform)
PURITY (HPLC)	98% to 105% plus as specified.
TOXICITY
USE	Ajmalicine is mainly used as an Anti-hypertensive agent and also reduce blood pressure Anti-ischemic (Cerebal and peripheral)